A Bayesian Breath of Fresh Air for Myocardial Salvage

نویسندگان

  • Hung Q. Ly
  • Jean-Francois Tanguay
چکیده

In North America, every 25 seconds someone will have a coronary event and every minute someone will die of one.1 ST elevation myocardial infarction (STEMI) is the most dramatic manifestation of coronary artery disease and remains as one of the most important causes of mortality in the industrialized world. Prompt and successful reperfusion therapy (either pharmacologically with use of fibrinolytic therapy or mechanically with primary percutaneous coronary intervention [PCI]) is currently the cornerstone of acute management of STEMI to salvage ischemic myocardium and limit infarct size. Although undoubtedly beneficial, reperfusion of an occluded artery represents “a double-edge sword,”2 because restoration of epicardial coronary flow initiates a series of complex biochemical and molecular phenomena, which will ultimately mitigate myocardial healing. Thus, with reperfusion comes reperfusion injury.3

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Superoxygen therapy: a Bayesian breath of fresh air for myocardial salvage.

In North America, every 25 seconds someone will have a coronary event and every minute someone will die of one.1 ST elevation myocardial infarction (STEMI) is the most dramatic manifestation of coronary artery disease and remains as one of the most important causes of mortality in the industrialized world. Prompt and successful reperfusion therapy (either pharmacologically with use of fibrinoly...

متن کامل

Bright-blood T2-weighted MRI has higher diagnostic accuracy than dark-blood short tau inversion recovery MRI for detection of acute myocardial infarction and for assessment of the ischemic area at risk and myocardial salvage.

BACKGROUND T2-Weighted MRI reveals myocardial edema and enables estimation of the ischemic area at risk and myocardial salvage in patients with acute myocardial infarction (MI). We compared the diagnostic accuracy of a new bright-blood T2-weighted with a standard black blood T2-weighted MRI in patients with acute MI. METHODS AND RESULTS A breath-hold, bright-blood T2-weighted, Acquisition for...

متن کامل

The Relationship between Air Quality and Cases of Myocardial Infarction in Yazd in 2016

Introduction: Air pollution is now one of the greatest environmental hazards to human health in the world. The aim of this study determines the relationship between air quality and cases of myocardial infarction in Yazd. Methods: This Ecological study was performed in Yazd, Iran. In this study, all individuals who referred to emergency cases with myocardial infarction in Yazd in one year from ...

متن کامل

Comparison of three commercially available activated charcoal canisters for passive scavenging of waste isoflurane during conventional rodent anesthesia.

Chronic, low-level exposure to waste anesthetic gases has been linked to increased incidences of neurologic and reproductive dysfunction, hepatic and renal toxicity, and neoplasia in humans. We have shown previously that one brand of activated charcoal canister (F/Air) used for passive scavenging of halogenated gases does not completely remove isoflurane during anesthetic protocols used in conv...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2009